This paper aims to explore the ambiguous and equivocal meanings of toxic substances as both symbols and entities in White Noise through the concept of hyperobjects by Timothy Morton. Niodine D in the novel shares the main features of hyperobjects; viscosity, phasing, temporally undulation, unlocality, interobjectivity. Because hyperobjects exceed the recognizable range of human senses of space and time, it is extremely difficult to understand them with the anthrophocentric standards and traditional ways of thinking. Niodine D has been often interpreted as a symbol to reveal the postmodern phenomenon that representations replace realities, which is caused from its nature as a hyperobject. It is impossible to escape or eliminate it because of its viscosity. Jack Gladney tries to find a solution by relying upon the power of modern technology, but it fails to grasp its natures and influences. Niodine D prompts Jack Gladney to awake from the illusion that rational reason can provide proper solutions for all the problems including ecological disasters. It requires human to recognize the limit of rational reason and reconsider the interconnected relationship of human and non-human elements.